Ethyl 2-aminopyridine-5-carboxylatel - Names and Identifiers
Ethyl 2-aminopyridine-5-carboxylatel - Physico-chemical Properties
Molecular Formula | C8H10N2O2
|
Molar Mass | 166.18 |
Density | 1.192±0.06 g/cm3(Predicted) |
Melting Point | 145-147 |
Boling Point | 314.7±22.0 °C(Predicted) |
Flash Point | 144.1°C |
Vapor Presure | 0.000457mmHg at 25°C |
pKa | 4.88±0.13(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
MDL | MFCD04972544 |
Ethyl 2-aminopyridine-5-carboxylatel - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36 - Irritating to the eyes
|
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
Hazard Note | Irritant |
Ethyl 2-aminopyridine-5-carboxylatel - Introduction
Ethyl 6-aminonicotinate, also known as ethylated 6-aminonicotinate, is an organic compound. The following is a description of its nature, use, preparation and safety information:
1. nature:
-Appearance: White or yellowish crystalline or powdery solid.
-Chemical formula: C9H10N2O2
-Molecular weight: 178.19g/mol
-Solubility: It has good solubility, soluble in most organic solvents such as ethanol and dimethylformamide, and slightly soluble in water.
2. use:
-Pharmaceutical field: Ethyl 6-aminonicotinate can be used as a synthetic drug intermediate for the preparation of some biologically active compounds, such as anti-inflammatory drugs and anti-tumor drugs.
-Scientific research field: Ethyl 6-aminonicotinate is also commonly used in organic synthetic chemistry research as an important raw material and reagent.
3. Preparation method:
- Ethyl 6-aminonicotinate can be prepared by reacting 6-aminonicotinate with acetic anhydride or ethyl acetate. The reaction may be carried out in a solvent with the addition of a desired catalyst such as metaphosphoric acid or zinc chloride. The reaction temperature is generally carried out at room temperature.
-After preparation, the pure product can be obtained by crystallization purification.
4. Safety Information:
- Ethyl 6-aminonicotinate is generally considered to have less impact on the human body under normal conditions of use. However, as a chemical substance, it is still necessary to pay attention to safe operation.
-When using, wear appropriate protective gloves and glasses to avoid skin contact and inhalation.
-Avoid reacting with strong oxidants or strong acids to avoid dangerous substances or fire.
-Store away from fire and heat sources, and store in a sealed container.
Last Update:2024-04-09 02:00:46